Autologous cancer vaccine treatment
What is autologous cancer vaccine therapy?
This is a type of immunotherapy that aims to induce a specific immune response against cancer in the body by administering a vaccine made from the patient's own cancer tissue, thereby achieving an anti-tumor effect.
This treatment is carried out under technical support from CellMedicine, Inc.
Mechanism of action of autologous cancer vaccine therapy
Administered cancer vaccines are thought to exert their antitumor effects in the following ways:
Cancer vaccine administered intradermally
Antigen-presenting cells in the skin, such as dendritic cells and macrophages, consume the cancer vaccine.
Antigen-presenting cells that have consumed the cancer vaccine migrate to nearby lymph nodes
Antigen presentation in the transferred lymph nodes
Proliferates and activates specific CTLs (Cytotoxic T Lymphocytes) that can respond to the presented antigens
The proliferated and activated specific CTLs migrate to the cancer site and kill the cancer cells.
Treatment flow, treatment period and number of sessions
Step 1: Interview and examination
Step 2: Provide 2g of tumor tissue (formalin-fixed tissue or paraffin-embedded block)
Step 3: Autologous cancer vaccine production (outsourced, about 5 days)
Step 4: Vaccinate according to the following schedule:
Fees (private medical treatment)
The treatment plan will vary depending on the patient's condition and symptoms, so we will decide after you have undergone an examination and tests.
Side effects of autologous cancer vaccine
Common side effects include localized redness, swelling, induration, and fever, but these are all temporary.
A rare severe side effect is the possibility of anaphylactic shock, although no cases of anaphylactic shock have been reported to date.
未承認医薬品等を用いた自由診療について
- Indicate that it is an unapproved drug, etc., and indicate the acquisition route, etc.
Autologous cancer vaccines have not been approved under the Pharmaceutical and Medical Device Act. In Japan, unapproved drugs and medical devices can be used at the doctor's own risk.
Availability of domestically approved drugs, etc.
Currently, there are no other drugs approved in Japan that have the same properties as the one used in this treatment.
Information on safety in foreign countries
Currently, there is no information regarding safety in other countries.